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Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Cash flows from operating activities    
Net loss $ (18,218) $ (76,333)
Adjustments to reconcile net loss to net cash used in operating activities    
Depreciation and amortization 498 1,060
Write-off of acquired in-process research & development   38,313
Stock-based compensation expense 3,399 16,139
Changes in assets and liabilities, net of acquisition    
Prepaid expenses and other assets (2,782) (224)
Accounts payable 652 (1,744)
Deferred revenue (146) (1,371)
Accrued and other liabilities (484) (5,097)
Net cash used in operating activities (17,081) (29,257)
Cash flows from investing activities    
Purchase of property and equipment   (33)
Cash paid to acquire in-process research & development   (2,076)
Cash acquired in the merger transaction   5,277
Net cash provided by investing activities   3,168
Cash flows from financing activities    
Inducement on build-to-suit lease obligation   1,896
Proceeds from issuance of common stock, net of issuance costs 25,127  
Proceeds from issuance of common stock in connection with employee benefit plans and exercise of stock options 123 52
Net cash provided by financing activities 25,250 1,948
Net increase (decrease) in cash, cash equivalents and restricted cash 8,169 (24,141)
Cash, cash equivalents and restricted cash at beginning of period 59,388 83,529
Cash, cash equivalents and restricted cash at end of period 67,557 59,388
Supplemental disclosure of noncash items    
Issuance of common stock for the merger transaction   $ 37,331
Property and equipment recorded upon adoption of ASU 2016-02 $ 2,151