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Summary of Significant Accounting Policies - Additional Information (Detail)
1 Months Ended 3 Months Ended 6 Months Ended 12 Months Ended
Jul. 31, 2016
USD ($)
Jun. 30, 2019
USD ($)
Jun. 30, 2018
Jun. 30, 2019
USD ($)
Segment
Jun. 30, 2018
USD ($)
Dec. 31, 2018
USD ($)
Jan. 01, 2019
USD ($)
Significant Accounting Policies [Line Items]              
Cash and cash equivalents   $ 48,384,000   $ 48,384,000   $ 56,992,000  
Accumulated deficit   (459,641,000)   (459,641,000)   (450,565,000)  
Working capital   47,400,000   $ 47,400,000      
Number of operating segment | Segment       1      
Cash and cash equivalents maturity period       Three months or less      
Impairments of long-lived assets       $ 0   0  
Revenue from product development award   $ 3,054,000   $ 4,753,000      
Type of Revenue [Extensible List]   us-gaap:GrantMember us-gaap:GrantMember us-gaap:GrantMember us-gaap:GrantMember    
Unbilled receivable   $ 2,000,000   $ 2,000,000      
Cash flows from financing activities       13,000 $ 1,931,000    
Build-to-suit lease asset           8,651,000  
Build-to-suit lease obligation           $ 7,324,000  
Operating lease ROU assets   9,501,000   9,501,000      
Operating lease obligation   11,500,000   11,500,000      
ASU 2016-02 [Member]              
Significant Accounting Policies [Line Items]              
Operating lease ROU assets             $ 10,400,000
Leasehold improvements             2,100,000
Operating lease obligation             12,600,000
ASU 2016-02 [Member] | Restatement Adjustment [Member]              
Significant Accounting Policies [Line Items]              
Accumulated deficit             1,300,000
Cash flows from investing activities         (1,900,000)    
Cash flows from financing activities         $ 1,900,000    
Deferred rent             (100,000)
ASU 2016-02 [Member] | Restatement Adjustment [Member] | 1020 Marsh Road, Menlo Park, California [Member]              
Significant Accounting Policies [Line Items]              
Build-to-suit lease asset             (8,600,000)
Build-to-suit lease obligation             $ (7,300,000)
Cancer Prevention & Research Institute of Texas [Member]              
Significant Accounting Policies [Line Items]              
Revenue from product development award $ 20,000,000            
Cancer Prevention & Research Institute of Texas [Member] | Aravive Biologics [Member]              
Significant Accounting Policies [Line Items]              
Revenue from product development award       $ 4,800,000      
Type of Revenue [Extensible List]       us-gaap:GrantMember      
Grant [Member] | Cancer Prevention & Research Institute of Texas [Member] | Aravive Biologics [Member] | Prepaids and Other Current Assets [Member]              
Significant Accounting Policies [Line Items]              
Unbilled receivable   $ 2,000,000   $ 2,000,000      
Assembled Workforce [Member]              
Significant Accounting Policies [Line Items]              
Estimated useful life of intangible assets       3 years      
Minimum [Member]              
Significant Accounting Policies [Line Items]              
Property and equipment estimated useful lives       3 years      
Maximum [Member]              
Significant Accounting Policies [Line Items]              
Property and equipment estimated useful lives       5 years