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Net Loss per Share of Common Stock - Summary of Computation of Basic and Diluted Net Loss Per Share (Detail) - USD ($)
$ / shares in Units, shares in Thousands, $ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2017
Sep. 30, 2016
Sep. 30, 2017
Sep. 30, 2016
Earnings Per Share [Abstract]        
Net loss $ (49,788) $ (27,335) $ (116,107) $ (73,684)
Weighted-average shares used to compute basic and diluted net loss per share 35,680 29,574 35,336 29,495
Basic and diluted net loss per common share $ (1.40) $ (0.92) $ (3.29) $ (2.50)