Summary of Significant Accounting Policies (Tables)

6 Months Ended

Jun. 30, 2016

Accounting Policies [Abstract]

Schedule of Estimated Stock-Based Compensation Expense

Stock-based compensation expense, net of estimated forfeitures, is reflected in the condensed consolidated statements of operations and comprehensive loss as follows (in thousands):

	Three Months Ended				Six Months Ended
	June 30,				June 30,
	2016		2015		2016		2015
Operating Expenses
Research and development	$	1,020	$	632	$	1,604	$	1,236
General and administrative		1,995		3,605		3,773		4,989
Total	$	3,015	$	4,237	$	5,377	$	6,225