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Summary of Significant Accounting Policies - Additional Information (Detail)
3 Months Ended 12 Months Ended
Mar. 31, 2016
USD ($)
Segment
Dec. 31, 2015
USD ($)
Mar. 31, 2015
USD ($)
Dec. 31, 2014
USD ($)
Significant Accounting Policies [Line Items]        
Cash and cash equivalents $ 160,933,000 $ 182,069,000 $ 230,261,000 $ 170,566,000
Accumulated deficit (217,667,000) (193,436,000)    
Working capital $ 153,900,000      
Number of operating segment | Segment 1      
Cash and cash equivalents maturity period Three months or less      
Impairments of long-lived assets $ 0 $ 0    
Minimum [Member]        
Significant Accounting Policies [Line Items]        
Property and equipment estimated useful lives 3 years      
Maximum [Member]        
Significant Accounting Policies [Line Items]        
Property and equipment estimated useful lives 5 years      
Percentage for the amount of benefit realized upon ultimate settlement 50.00%