Quarterly Results (Unaudited)

12 Months Ended

Dec. 31, 2014

Quarterly Financial Information Disclosure [Abstract]

Quarterly Results (Unaudited)

16. Quarterly Results (Unaudited)

The following table is in thousands, except per share amounts:

	Quarters Ended
	March 31,			June 30,			September 30,			December 31,
	2014			2014			2014			2014
Consolidated Statement of operations data:
Operating expenses
Research and development	$	4,869		$	5,622		$	10,515		$	11,602
General and administrative		2,714			2,877			3,577			4,338
Total operating expenses		7,583			8,499			14,092			15,940
Loss from operations		(7,583	)		(8,499	)		(14,092	)		(15,940	)
Interest income		—			40			50			43
Interest expense		—			—			—			—
Other income (expense), net		(11,843	)		(141	)		208			244
Net loss and comprehensive loss		(19,426	)		(8,600	)		(13,834	)		(15,653	)
Deemed dividend related to beneficial conversion      feature of convertible preferred stock		(25,559	)		-			-			-
Net loss attributable to common stockholders	$	(44,985	)	$	(8,600	)	$	(13,834	)	$	(15,653	)
Net loss per basic and diluted share attributable to      common stockholders	$	(16.13	)	$	(0.36	)	$	(0.57	)	$	(0.65	)
Weighted-average common shares used to compute      basic and diluted net loss per share		2,788,087			24,194,808			24,194,808			24,215,018
	Year Ended December 31,
	March 31,			June 30,			September 30,			December 31,
	2013			2013			2013			2013
Statement of operations data:
Operating expenses
Research and development	$	3,499		$	3,326		$	4,576		$	3,454
General and administrative		682			656			685			2,405
Total operating expenses		4,181			3,982			5,261			5,859
Loss from operations		(4,181	)		(3,982	)		(5,261	)		(5,859	)
Interest income		—			—			—			1
Interest expense		(128	)		—			—			—
Other income (expense), net		290			327			252			44
Net loss and comprehensive loss		(4,019	)		(3,655	)		(5,009	)		(5,814	)
Deemed dividend related to beneficial conversion      feature of convertible preferred stock		-			-			-			-
Net loss attributable to common stockholders	$	(4,019	)	$	(3,655	)	$	(5,009	)	$	(5,814	)
Net loss per basic and diluted share attributable to      common stockholders	$	(30.23	)	$	(24.74	)	$	(19.98	)	$	(4.62	)
Weighted-average common shares used to compute      basic and diluted net loss per share		132,969			147,713			250,745			1,257,250