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Note 1 - Formation and Business of the Company (Details Textual) - USD ($)
1 Months Ended 3 Months Ended 6 Months Ended 12 Months Ended 32 Months Ended 41 Months Ended 42 Months Ended
Nov. 06, 2020
Jun. 01, 2016
Oct. 31, 2022
Jun. 30, 2023
Jun. 30, 2022
Jun. 30, 2021
Jun. 30, 2023
Jun. 30, 2022
Dec. 31, 2022
Jun. 30, 2023
Nov. 30, 2019
Nov. 30, 2019
Aug. 31, 2021
Revenue from Contract with Customer, Excluding Assessed Tax, Total       $ 1,274,000 $ 1,615,000   $ 2,764,000 $ 2,707,000          
Cancer Prevention and Research Institute of Texas [Member]                          
Revenue from Contract with Customer, Excluding Assessed Tax, Total                     $ 20,000,000    
Percentage of Cash Required to Raise in Matching Funds   50.00%                      
Cash Required to Raise in Matching Funds   $ 10,000,000.0                      
Matching Funds Required to Raise, Project Term (Year)   3 years                      
Cash Required in Matching Funds, Amount Raised                       $ 10,000,000.0  
Percentage of Grant Award Proceeds Required to Pay   400.00%                      
3D Medicines, Inc [Member]                          
Proceeds from Collaborators                 $ 15,000,000 $ 27,000,000      
Proceeds from Milestone Achievement     $ 6,000,000     $ 6,000,000              
Collaborative Agreement, Expected Milestone Payments to be Received                         $ 3,000,000
3D Medicines, Inc [Member] | Mainland China,Taiwan, Hong Kong and Macau [Member]                          
Proceeds from Collaborators $ 12,000,000                        
Leland Stanford Junior University [Member]                          
Maximum Milestone Payments Upon Achievement of Clinical and Regulatory Milestones       $ 1,000,000     $ 1,000,000     $ 1,000,000