Condensed Consolidated Statements of Stockholders' Equity (Unaudited) - USD ($) $ in Thousands	Registered Direct Offering [Member] Common Stock [Member]	Registered Direct Offering [Member] Additional Paid-in Capital [Member]	Registered Direct Offering [Member] Retained Earnings [Member]	Registered Direct Offering [Member]	Direct Offering [Member] Common Stock [Member]	Direct Offering [Member] Additional Paid-in Capital [Member]	Direct Offering [Member] Retained Earnings [Member]	Direct Offering [Member]	At-the-market Offering [Member] Common Stock [Member]	At-the-market Offering [Member] Additional Paid-in Capital [Member]	At-the-market Offering [Member] Retained Earnings [Member]	At-the-market Offering [Member]	Common Stock [Member]	Additional Paid-in Capital [Member]	Retained Earnings [Member]	Total
Balances (in shares) at Dec. 31, 2020													16,481,099
Balances at Dec. 31, 2020													$ 2	$ 548,707	$ (500,654)	$ 48,055
Issuance of common stock, net (in shares)					2,875,000				884,695
Issuance of common stock, net					$ 0	$ 20,866	$ 0	$ 20,866	$ 0	$ 7,034	$ 0	$ 7,034
Stock-based compensation													0	505	0	505
Net loss													$ 0	0	(8,004)	(8,004)
Issuance of common stock upon exercise of options (in shares)													77,858
Issuance of common stock upon exercise of options													$ 0	260	0	260
Balances (in shares) at Mar. 31, 2021													20,318,652
Balances at Mar. 31, 2021													$ 2	577,372	(508,658)	68,716
Balances (in shares) at Dec. 31, 2020													16,481,099
Balances at Dec. 31, 2020													$ 2	548,707	(500,654)	48,055
Net loss																(26,195)
Balances (in shares) at Sep. 30, 2021													20,904,499
Balances at Sep. 30, 2021													$ 2	581,183	(526,849)	54,336
Balances (in shares) at Mar. 31, 2021													20,318,652
Balances at Mar. 31, 2021													$ 2	577,372	(508,658)	68,716
Issuance of common stock, net (in shares)									314,983
Issuance of common stock, net									$ 0	1,816	0	1,816
Stock-based compensation													0	540	0	540
Net loss													$ 0	0	(7,105)	(7,105)
Issuance of common stock under employee benefit plans (in shares)													17,275
Issuance of common stock under employee benefit plans													$ 0	71	0	71
Issuance of common stock upon exercise of options (in shares)													63,094
Issuance of common stock upon exercise of options													$ 0	20	0	20
Balances (in shares) at Jun. 30, 2021													20,714,004
Balances at Jun. 30, 2021													$ 2	579,819	(515,763)	64,058
Issuance of common stock, net (in shares)													182,995
Issuance of common stock, net													$ 0	732	0	732
Stock-based compensation													0	627	0	627
Net loss													$ 0	0	(11,086)	(11,086)
Issuance of common stock upon exercise of options (in shares)													7,500
Issuance of common stock upon exercise of options													$ 0	5	0	5
Balances (in shares) at Sep. 30, 2021													20,904,499
Balances at Sep. 30, 2021													$ 2	581,183	(526,849)	54,336
Balances (in shares) at Dec. 31, 2021													21,039,594
Balances at Dec. 31, 2021													$ 2	582,025	(539,805)	42,222
Issuance of common stock, net (in shares)	3,185,216								54,763
Issuance of common stock, net	$ 0	$ 9,291	$ 0	$ 9,291					$ 0	$ 123	$ 0	$ 123
Stock-based compensation													0	620	0	620
Net loss													$ 0	0	(13,057)	(13,057)
Balances (in shares) at Mar. 31, 2022													24,279,573
Balances at Mar. 31, 2022													$ 2	592,059	(552,862)	39,199
Balances (in shares) at Dec. 31, 2021													21,039,594
Balances at Dec. 31, 2021													$ 2	582,025	(539,805)	42,222
Net loss																$ (47,197)
Issuance of common stock upon exercise of options (in shares)																(0)
Balances (in shares) at Sep. 30, 2022													30,518,269
Balances at Sep. 30, 2022													$ 3	602,041	(587,002)	$ 15,042
Balances (in shares) at Mar. 31, 2022													24,279,573
Balances at Mar. 31, 2022													$ 2	592,059	(552,862)	39,199
Stock-based compensation													0	725	0	725
Net loss													$ 0	0	(18,477)	(18,477)
Issuance of common stock upon exercise of pre-funded warrants (in shares)													6,210,480
Issuance of common stock upon exercise of pre-funded warrants													$ 1	8,592	0	8,593
Issuance of common stock under employee benefit plans (in shares)													28,216
Issuance of common stock under employee benefit plans													$ 0	26	0	26
Balances (in shares) at Jun. 30, 2022													30,518,269
Balances at Jun. 30, 2022													$ 3	601,402	(571,339)	30,066
Stock-based compensation													0	639	0	639
Net loss													$ 0	0	(15,663)	(15,663)
Balances (in shares) at Sep. 30, 2022													30,518,269
Balances at Sep. 30, 2022													$ 3	$ 602,041	$ (587,002)	$ 15,042