Consolidated Statements of Operations - USD ($) shares in Thousands, $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020
Revenue
Total revenue	$ 7,442	$ 5,685
Operating expenses
Research and development	37,541	17,620
General and administrative	10,550	13,065
Loss on impairment of long-lived assets	0	5,784
Total operating expenses	48,091	36,469
Loss from operations	(40,649)	(30,784)
Interest income	37	255
Other income (expense), net	1,461	(14)
Net loss	$ (39,151)	$ (30,543)
Net loss per share - basic and diluted (in dollars per share)	$ (1.95)	$ (1.93)
Weighted-average common shares used to compute basic and diluted net loss per share (in shares)	20,070	15,790
Collaborative Arrangement [Member]
Revenue
Total revenue	$ 7,442	$ 5,685