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Note 1 - Formation and Business of the Company (Details Textual) - USD ($)
1 Months Ended 2 Months Ended 3 Months Ended 6 Months Ended 8 Months Ended 42 Months Ended
Nov. 06, 2020
Jun. 01, 2016
Apr. 30, 2021
Jul. 31, 2016
Dec. 31, 2020
Jun. 30, 2021
Jun. 30, 2020
Jun. 30, 2021
Jun. 30, 2020
Jun. 30, 2021
Nov. 30, 2019
Jul. 31, 2021
Revenue from Contract with Customer, Excluding Assessed Tax, Total           $ 3,789,000 $ 0 $ 4,045,000 $ 0      
3D Medicines, Inc [Member]                        
Proceeds from Collaborators         $ 12,000,000 6,000,000   6,000,000   $ 18,000,000    
Proceeds from Milestone Achievement     $ 6,000,000                  
3D Medicines, Inc [Member] | Subsequent Event [Member]                        
Collaborative Agreement, Expected Milestone Payments to be Received                       $ 3,000,000
3D Medicines, Inc [Member] | Mainland China,Taiwan, Hong Kong and Macau [Member]                        
Proceeds from Collaborators $ 12,000,000                      
Cancer Prevention and Research Institute of Texas [Member]                        
Revenue from Contract with Customer, Excluding Assessed Tax, Total       $ 20,000,000.0                
Percentage of Cash Required to Raise in Matching Funds   50.00%                    
Cash Required to Raise in Matching Funds   $ 10,000,000.0                    
Matching Funds Required to Raise, Project Term (Year)   3 years                    
Cash Required in Matching Funds, Amount Raised                     $ 10,000,000.0  
Percentage of Grant Award Proceeds Required to Pay   400.00%                    
Maximum Percentage of Grant Award Proceeds Required to Pay Thereafter Until Government Exclusivity Maintained   1.00%                    
Leland Stanford Junior University [Member]                        
Maximum Milestone Payments Upon Achievement of Clinical and Regulatory Milestones           $ 1,000,000   $ 1,000,000   $ 1,000,000