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Note 8 - Stock Based Awards (Tables)
6 Months Ended
Jun. 30, 2021
Notes Tables  
Share-based Payment Arrangement, Option, Activity [Table Text Block]
          

Weighted

     
          

Average

     
      

Weighted

  

Remaining

  

Aggregate

 
      

Average

  

Contractual

  

Intrinsic

 
  

Number of

  

Exercise

  

Life

  

Value

 
  

Shares

  

Price

  

(in years)

  

(in thousands)

 

Balances, January 1, 2021

  2,173,776  $9.59         

Options granted

  608,950   6.02         

Options cancelled

  (343,537)  43.89         

Options exercised

  (140,952)  1.98         

Balances, June 30, 2021

  2,298,237  $3.99   7.1  $5,905 

Outstanding and expected to vest as of June 30, 2021

  2,125,891  $3.77   6.9  $5,871 

Exercisable as of June 30, 2021

  1,373,881  $2.12   5.6  $5,707 
Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
  

June 30,

  

June 30,

 
  

2021

  

2020

 

Expected volatility

  113.4%  78.1%

Risk-free interest rate

  0.7%  0.8%

Dividend yield

  0.0%  0.0%

Expected life (in years)

  6.1   3.9