TEXT-EXTRACT 2 filename2.txt United States securities and exchange commission logo November 22, 2022 Gail McIntyre Chief Executive Officer Aravive, Inc. River Oaks Tower 3730 Kirby Drive, Suite 1200 Houston, Texas 77098 Re: Aravive, Inc. Registration Statement on Form S-3 Filed November 18, 2022 File No. 333-268471 Dear Gail McIntyre: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Joshua Gorsky at 202-551-7836 with any questions. Sincerely, Division of Corporation Finance Office of Life Sciences cc: Leslie Marlow, Esq.