The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | |||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | ||||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | FIGI | (to the nearest dollar) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| ADAPTIMMUNE THERAPEUTICS PLC | SPONDS ADR | 00653A107 | 4,094,023 | 17,079,778 | SH | DFND | 17,079,778 | 0 | 0 | |||
| ARCELLX INC | COMMON STOCK | 03940C100 | 246,625,503 | 3,745,262 | SH | DFND | 3,745,262 | 0 | 0 | |||
| AURINIA PHARMACEUTICALS INC | COM | 05156V102 | 33,624,494 | 3,969,834 | SH | DFND | 3,969,834 | 0 | 0 | |||
| BLACK DIAMOND THERAPEUTICS I | COM | 09203E105 | 11,032,917 | 4,448,757 | SH | DFND | 4,448,757 | 0 | 0 | |||
| CELCUITY INC | COM | 15102K100 | 30,628,384 | 2,294,261 | SH | DFND | 2,294,261 | 0 | 0 | |||
| CHAMPIONS ONCOLOGY INC | COM NEW | 15870P307 | 12,630,116 | 1,713,720 | SH | DFND | 1,713,720 | 0 | 0 | |||
| COURSERA INC | COM | 22266M104 | 112,721,656 | 12,867,769 | SH | DFND | 12,867,769 | 0 | 0 | |||
| CRISPR THERAPEUTICS AG | NAMEN AKT | H17182108 | 77,233,219 | 1,587,854 | SH | DFND | 1,587,854 | 0 | 0 | |||
| CVRX INC | COM | 126638105 | 11,913,368 | 2,026,083 | SH | DFND | 2,026,083 | 0 | 0 | |||
| GOSSAMER BIO INC | COM | 38341P102 | 22,254,432 | 18,093,034 | SH | DFND | 18,093,034 | 0 | 0 | |||
| IKENA ONCOLOGY INC | COM | 45175G108 | 804,084 | 600,063 | SH | DFND | 600,063 | 0 | 0 | |||
| INOZYME PHARMA INC | COM | 45790W108 | 9,750,756 | 2,437,689 | SH | DFND | 2,437,689 | 0 | 0 | |||
| INVENTIVA SA | ADS | 46124U107 | 4,665,649 | 1,462,586 | SH | DFND | 1,462,586 | 0 | 0 | |||
| KORRO BIO INC | COM | 500946108 | 13,624,005 | 1,090,793 | SH | DFND | 1,090,793 | 0 | 0 | |||
| MARKER THERAPEUTICS INC | COM NEW | 57055L206 | 2,487,287 | 1,625,678 | SH | DFND | 1,625,678 | 0 | 0 | |||
| MBX BIOSCIENCES INC | COM | 55287L101 | 41,241,285 | 3,614,486 | SH | DFND | 3,614,486 | 0 | 0 | |||
| MONTE ROSA THERAPEUTICS INC | COM | 61225M102 | 34,692,264 | 7,692,298 | SH | DFND | 7,692,298 | 0 | 0 | |||
| NEUEHEALTH INC | COM NEW | 10920V404 | 18,815,727 | 2,726,917 | SH | DFND | 2,726,917 | 0 | 0 | |||
| NKARTA INC | COM | 65487U108 | 5,924,176 | 3,568,781 | SH | DFND | 3,568,781 | 0 | 0 | |||
| OMADA HEALTH INC | COM | 68170A108 | 6,663,305 | 364,115 | SH | DFND | 364,115 | 0 | 0 | |||
| ONKURE THERAPEUTICS INC | COM CL A | 68277Q105 | 1,143,730 | 478,548 | SH | DFND | 478,548 | 0 | 0 | |||
| ORIC PHARMACEUTICALS INC | COM | 68622P109 | 41,804,003 | 4,118,621 | SH | DFND | 4,118,621 | 0 | 0 | |||
| PHATHOM PHARMACEUTICALS INC | COM | 71722W107 | 18,798,021 | 1,960,169 | SH | DFND | 1,960,169 | 0 | 0 | |||
| RHYTHM PHARMACEUTICALS INC | COM | 76243J105 | 183,880,120 | 2,909,956 | SH | DFND | 2,909,956 | 0 | 0 | |||
| SAVARA INC | COM | 805111101 | 55,794,482 | 24,471,264 | SH | DFND | 24,471,264 | 0 | 0 | |||
| SENTI BIOSCIENCES INC | COM NEW | 81726A209 | 7,966,548 | 3,775,615 | SH | DFND | 3,775,615 | 0 | 0 | |||
| SYNLOGIC INC | COM NEW | 87166L209 | 3,711,921 | 2,922,772 | SH | DFND | 2,922,772 | 0 | 0 | |||
| TREVI THERAPEUTICS INC | COM | 89532M101 | 72,325,588 | 13,222,228 | SH | DFND | 13,222,228 | 0 | 0 | |||
| VERONA PHARMA PLC | SPONSERED ADS | 925050106 | 214,047,592 | 2,263,138 | SH | DFND | 2,263,138 | 0 | 0 | |||
| WHEELS UP EXPERIENCE INC | COM CL A | 96328L205 | 113,554 | 106,125 | SH | DFND | 106,125 | 0 | 0 | |||
| X4 PHARMACEUTICALS INC | COM | 98420X103 | 949,162 | 499,559 | SH | DFND | 499,559 | 0 | 0 | |||
| ZENAS BIOPHARMA INC | COM | 98937L105 | 26,489,737 | 2,733,719 | SH | DFND | 2,733,719 | 0 | 0 | |||