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Debt Obligations - 2027 Term Loan - Narrative (Details) $ in Thousands	1 Months Ended		3 Months Ended	6 Months Ended
	Mar. 31, 2022 USD ($)	Jan. 31, 2022 USD ($) item	Mar. 31, 2022 USD ($)	Jun. 30, 2022 USD ($)	Jan. 05, 2022 USD ($) tranche	Apr. 30, 2020 USD ($)	Feb. 29, 2016 USD ($)
Debt Instrument [Line Items]
Outstanding amount paid off				$ 81,750
Outstanding amount payoff				109,000
2027 Term Loans \| BioPharma Credit Investments V GP LLC
Debt Instrument [Line Items]
Principal amount					$ 300,000
Number of tranches \| tranche					4
Net carrying value				196,037
Stated interest rate		8.25%
Quarterly payments \| item		5
Loan agreement covenants, minimum trailing twelve month net sales for current quarter		$ 200,000
Loan agreement covenants, minimum trailing twelve month net sales for the quarter ended March 30, 2024		210,000
Loan agreement covenants, minimum trailing twelve-month net sales for the quarter ended June 30, 2024		230,000
Loan agreement covenants, minimum trailing twelve-month net sales for the quarter ended September 30, 2024		270,000
Loan agreement covenants, minimum trailing twelve-month net sales for the quarter ended December 31, 2024 and thereafter		$ 300,000
Mandatory prepayment term		10 days
Debt discounts and issuance costs		$ 6,800
Remaining unamortized debt discount and debt offering costs				$ 3,963
Effective interest rate				9.25%
2027 Term Loans \| BioPharma Credit Investments V GP LLC \| Three-month LIBOR
Debt Instrument [Line Items]
Spread on variable rate		1.00%
2027 Term Loans \| Additional facility amount \| BioPharma Credit Investments V GP LLC
Debt Instrument [Line Items]
Principal amount		$ 100,000
Tranche A Loan, funded January 5, 2022 \| BioPharma Credit Investments V GP LLC
Debt Instrument [Line Items]
Principal amount					$ 100,000
Debt discounts and issuance costs		7,800
Tranche B Loan, funded no later than April 1, 2022 \| BioPharma Credit Investments V GP LLC
Debt Instrument [Line Items]
Principal amount	$ 100,000		$ 100,000
Debt discounts and issuance costs			2,300
Convertible notes, Issuance Cost	$ 1,000		$ 1,000
Tranche C Loan, funded between April 1, 2022 and March 17, 2023 \| BioPharma Credit Investments V GP LLC
Debt Instrument [Line Items]
Principal amount		50,000
Tranche D Loan, funded between April 1, 2022 and March 17, 2023 \| BioPharma Credit Investments V GP LLC
Debt Instrument [Line Items]
Principal amount		50,000
1.5% Convertible Senior Subordinated Notes due 2026 \| Convertible Notes
Debt Instrument [Line Items]
Principal amount						$ 230,000
Net carrying value				$ 224,928
Stated interest rate						1.50%
Remaining unamortized debt discount and debt offering costs				$ 5,072
Effective interest rate				2.10%
1.5% Convertible Senior Subordinated Notes due 2026 \| BioPharma Credit Investments V GP LLC \| Scenario, Plan \| Minimum
Debt Instrument [Line Items]
Principal amount		50,000
8.2% Convertible Notes due 2022 \| Convertible Notes
Debt Instrument [Line Items]
Principal amount		100,000					$ 100,000
Stated interest rate	8.20%		8.20%				8.20%
Outstanding amount payoff	$ 111,100	111,100
2025 Term Loan
Debt Instrument [Line Items]
Net carrying value				$ 0
2025 Term Loan \| Convertible Notes
Debt Instrument [Line Items]
Principal amount		75,000
Outstanding amount paid off		$ 81,900
Tranche A and B Loans \| BioPharma Credit Investments V GP LLC
Debt Instrument [Line Items]
Remaining unamortized debt discount and debt offering costs				$ 4,000
Remaining term				4 years 6 months