Exhibit 99.38

MATERIAL CHANGE REPORT

Regulation 51-102 Respecting Continuous Disclosure Obligations
Form 51-102F3

1.	NAME AND ADDRESS OF COMPANY:
	THERATECHNOLOGIES INC. 2310 Alfred-Nobel Boulevard Montreal, Québec Canada H4S 2B4
2.	DATE OF MATERIAL CHANGE:
	September 1, 2010
3.	NEWS RELEASE:
	A news release was issued concerning this material change on September 1, 2010 on “Marketwire”. A copy of the news release is available at SEDAR website at www.sedar.com.
4.	SUMMARY OF MATERIAL CHANGE:
	On September 1, 2010, Theratechnologies Inc. (the “Company”) announced the appointment of a new president and chief executive officer who will assume his responsibilities in the coming months.
5.	FULL DESCRIPTION OF MATERIAL CHANGE:
	On September 1, 2010, the Company announced that Mr. John-Michel T. Huss was appointed as the new president and chief executive officer of the Company. Mr. Huss will assume his responsibilities in the coming months.
6.	RELIANCE ON SUBSECTION 7.1(2) OF REGULATION 51-102:
	Not applicable.
7.	OMITTED INFORMATION:
	Not applicable.
8.	SENIOR OFFICER:
	For further information, contact Jocelyn Lafond, Vice President, Legal Affairs, and Corporate Secretary of Theratechnologies Inc., at (514) 336-4804, ext. 288.
9.	DATE OF REPORT:
	September 1, 2010.