As filed with the Securities and Exchange Commission on or about February 12, 2013

1933 Act Registration No. 333-171933

1940 Act Registration No.   811-22523

United States

Securities and Exchange Commission

Washington, D.C. 20549

Form N-1A

Registration Statement Under the Securities Act of 1933 [   ]

Pre-Effective Amendment No. __ [   ]

Post-Effective Amendment No. 33 [X]

and/or

Registration Statement Under the Investment Company Act of 1940 [   ]

Amendment No. 34 [X]

Destra Investment Trust II

(Exact name of registrant as specified in charter)

901 Warrenville Road, Suite 15

Lisle, Illinois 60532

(Address of Principal Executive Offices) (Zip Code)

Registrant's Telephone Number, including Area Code: (630) 241-4200

	Copy to:
Nicholas Dalmaso	Morrison Warren, Esq.
Destra Investment Trust II	Chapman and Cutler LLP
901 Warrenville Road, Suite 15	111 West Monroe Street
Lisle, Illinois 60532	Chicago, Illinois 60603

(Name and Address of Agent for Service)

It is proposed that this filing will become effective (check appropriate box):

[X] immediately upon filing pursuant to paragraph (b)

[   ] on (date) pursuant to paragraph (b)

[   ] 60 days after filing pursuant to paragraph (a)(1)

[   ] on (date) pursuant to paragraph (a)(1)

[   ] 75 days after filing pursuant to paragraph (a)(2)

[   ] on (date) pursuant to paragraph (a)(2) of Rule 485.

If appropriate, check the following box:

[   ] this post-effective amendment designates a new effective date for a previously filed post-effective amendment.

This filing relates solely to the following Funds, each a series of the Registrant:

Destra Preferred and Income Securities Fund

Destra Focused Equity Fund

SIGNATURES

Pursuant to the requirements of the Securities Act of 1933, as amended, and the Investment Company Act of 1940, as amended, the Registrant certifies that it meets all of the requirements for effectiveness of this registration statement under Rule 485(b) under the Securities Act of 1933 and has duly caused this registration statement to be signed on its behalf by the undersigned, duly authorized, in the City of Lisle, and State of Illinois, on the 12th day of February, 2013.

Destra Investment Trust II

By:__/s/ Nicholas Dalmaso

Nicholas Dalmaso

Chief Executive Officer

Pursuant to the requirements of the Securities Act of 1933, this post-effective amendment to the registration statement has been signed below by the following persons in the capacities and on the date indicated:

Signature	Title		Date
/s/ Nicholas Dalmaso	Chief Executive Officer, Chairman, Secretary and Trustee		February 12, 2013
Nicholas Dalmaso
Diana S. Ferguson*	Trustee	} } } } } } }	By /s/ Nicholas Dalmaso
			Nicholas Dalmaso
William M. Fitzgerald, Sr.*	Trustee		Attorney-In-Fact February 12, 2013
Louis A. Holland, Jr.*	Lead Independent Trustee and Trustee

*An original power of attorney authorizing Nicholas Dalmaso and Morrison C. Warren to execute this registration statement, and amendments thereto, for each of the trustees of the Registrant on whose behalf this registration statement is filed, has been executed and has previously been filed with the Securities and Exchange Commission and is incorporated by reference herein.

Index of Exhibits

Exhibit Number	Exhibit
101.INS	XBRL Instance Document
101.SCH	XBRL Taxonomy Extension Schema Document
101.CAL	XBRL Taxonomy Extension Calculation Linkbase
101.DEF	XBRL Taxonomy Extension Definition Linkbase
101.LAB	XBRL Taxonomy Extension Labels Linkbase
101.PRE	XBRL Taxonomy Extension Presentation Linkbase