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Warrants (Details) $ / shares in Units, $ in Thousands					3 Months Ended	12 Months Ended
Warrants (Details) $ / shares in Units, $ in Thousands	Sep. 24, 2021 $ / shares shares	Jun. 22, 2020 $ / shares shares	Mar. 05, 2020 $ / shares shares	Jan. 03, 2020 Vote item $ / shares shares	Mar. 31, 2023 USD ($) $ / shares shares	Dec. 31, 2022 $ / shares shares	Jan. 31, 2023 $ / shares shares	Feb. 05, 2019 $ / shares shares
Warrants
Number of Shares Issuable					49,638,691
Change in fair value of warrant liability \| $					$ 50
Series X Preferred Stock
Warrants
Warrant to purchase shares of common stock					443
Conversion ratio					1,000
January 23 2017 Warrants
Warrants
Exercise price of warrant \| $ / shares					$ 0.01
Number of Shares Issuable					54,516
March 2020 Pre-funded Warrants
Warrants
Exercise price of warrant \| $ / shares					$ 0.001
Number of Shares Issuable					8,247,170
March 2020 Coverage Warrants
Warrants
Exercise price of warrant \| $ / shares					$ 2.11
Number of Shares Issuable					25,945,035
January 2023 Common Stock Warrants
Warrants
Warrant to purchase shares of common stock							65,301
Exercise price of warrant \| $ / shares					$ 0.680		$ 0.68
Number of Shares Issuable					65,301
January 2023 Series X Preferred Stock Warrants \| Series X Preferred Stock
Warrants
Warrant to purchase shares of common stock					443		443
Exercise price of warrant \| $ / shares					$ 678.48		$ 678.48
Conversion ratio					1,000		1,000
Feb 2019 warrants
Warrants
Purchase price per share \| $ / shares					$ 0.29
2017 Warrants
Warrants
Exercise price of warrant \| $ / shares					$ 1.055
Number of Shares Issuable					2,502,382
2019 Warrants
Warrants
Warrant to purchase shares of common stock								7,557,142
Exercise price of warrant \| $ / shares					$ 1.95			$ 1.95
Number of shares redeemed \| $					$ 100,000
Number of Shares Issuable					6,908,257
March 2020 Warrants
Warrants
Exercise price of warrant \| $ / shares						$ 0.001
Number of warrants or rights exercised						6,166,732
March 2020 Warrants \| Series A Preferred Stock
Warrants
Warrant to purchase shares of common stock			14,413,902
Exercise price of warrant \| $ / shares			$ 0.001
Common stock issued				1,421,801
Purchase price \| $ / shares				$ 10.54
Number of special voting stock \| Vote				1
Number of members to elect of board of directors \| item				1
March 2020 Warrants \| Series B Preferred Stock
Warrants
Exercise price of warrant \| $ / shares			$ 2.11
Common stock issued				1,137,442
Purchase price \| $ / shares				$ 10.55
Conversion of stock, shares issued			11,531,133
March 2020 Warrants \| Common Stock
Warrants
Number of shares issued upon exercise of warrants						6,161,000
September 2021
Warrants
Exercise price of warrant \| $ / shares	$ 0.001				$ 0.001	$ 0.001
Common stock issued	8,771,928
Number of warrants or rights exercised						2,855,898
Number of Shares Issuable					5,916,030
September 2021 \| Common Stock
Warrants
Common stock issued	27,568,072
Purchase price \| $ / shares	$ 2.85
Number of shares issued upon exercise of warrants						2,853,351
June 2020
Warrants
Exercise price of warrant \| $ / shares		$ 0.001				$ 0.001
Number of warrants or rights exercised						1,690,137
Number of Shares Issuable		2,250,000
June 2020 \| Common Stock
Warrants
Common stock issued		20,250,000
Purchase price \| $ / shares		$ 2.00
Number of shares issued upon exercise of warrants						1,688,571