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CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Cash flows from operating activities:    
Net loss $ (54,596) $ (40,587)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation expense 16 29
Amortization of contract asset   135
Change in right-of-use asset 399 392
Stock-based compensation expense 5,180 3,686
Foreign currency loss 608 379
Change in fair value of restricted stock liability   (204)
Changes in operating assets and liabilities:    
Prepaid expenses and other assets 416 (639)
Deferred tax asset 152 11
Research and development incentive receivable (1,009) (1,159)
Deferred costs   209
Accounts payable and accrued expenses 945 3,900
Deferred revenue   (1,500)
Lease liability (400) (406)
Other assets (755) 597
Net cash used in operating activities (49,044) (35,157)
Cash flows from financing activities:    
Proceeds from the issuance of common stock and prefunded warrants, net of offering costs - September 2021 Public Offering   97,222
Proceeds from the exercise of common stock warrants   993
Proceeds from the exercise of stock options   4
Payment of deferred costs (210) (184)
Net cash provided by (used in) financing activities (210) 98,035
Effect of exchange rate changes on cash and cash equivalents (162) (33)
Net increase (decrease) in cash and cash equivalents (49,416) 62,845
Cash and cash equivalents at beginning of period 114,916 52,071
Cash and cash equivalents at end of period 65,500 114,916
Supplemental disclosure of non-cash financing activities:    
Deferred costs in accounts payable and accrued expense - January 2023 Flame Merger 576  
Deferred costs in accounts payable and accrued expense - September 2021 Public Offering   210
Remeasurement of right-of-use asset and lease liability $ 609 $ 323