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Equity Incentive Plans (Details) - USD ($)
$ / shares in Units, $ in Thousands
3 Months Ended 9 Months Ended 12 Months Ended
Jan. 20, 2017
Sep. 30, 2022
Sep. 30, 2021
Sep. 30, 2022
Sep. 30, 2021
Dec. 31, 2021
Jun. 16, 2022
Options              
Outstanding balance at the beginning of the period (in shares)       8,525,618      
Granted (in shares)       3,900,000      
Forfeited (in shares)       (492,915)      
Outstanding balance at the end of the period (in shares)   11,932,703   11,932,703   8,525,618  
Options exercisable at the end of the period (in shares)   6,907,653   6,907,653      
Options vested and expected to vest at end of period (in shares)   11,932,703   11,932,703      
Weighted Average Exercise Price Per Share              
Outstanding balance at the beginning of the period (in dollars per share)       $ 4.48      
Granted (in dollars per share)       1.51      
Forfeited (in dollars per share)       2.17      
Outstanding balance at the end of the period (in dollars per share)   $ 3.60   3.60   $ 4.48  
Exercisable at the end of the period (in dollars per share)   5.01   5.01      
Options vested and expected to vest at end of the period (in dollars per share)   $ 3.60   $ 3.60      
Weighted Average Remaining Life in Years              
Outstanding balance       7 years 7 months 24 days   7 years 6 months 29 days  
Options exercisable at end of period       6 years 4 months 20 days      
Options vested and expected to vest at end of the period       7 years 7 months 24 days      
Aggregate Intrinsic Value              
Outstanding balance   $ 1   $ 1      
Options vested and expected to vest at end of the period   $ 1   $ 1      
Assumptions used to determine grant-date fair value              
Expected Volatility       82.70% 66.94%    
Weighted average risk-free interest rate       3.06% 0.81%    
Expected dividend yield       0.00% 0.00%    
Expected term (in years)       6 years 5 months 23 days 6 years 9 months 25 days    
Options unvested at end of period (in dollars per share)   $ 1.10 $ 1.37 $ 1.10 $ 1.37    
Expiration period       10 years      
unrecognized compensation cost related to non-vested stock options   $ 5,493   $ 5,493      
Weighted average period for recognition of compensation cost       2 years 3 months 21 days      
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Non vested, Weighted Average Grant Date Fair Value              
Outstanding at end(in dollars per share)   $ 1.10 $ 1.37 $ 1.10 $ 1.37    
Minimum              
Assumptions used to determine grant-date fair value              
Vesting period       3 years      
Maximum              
Assumptions used to determine grant-date fair value              
Vesting period       4 years      
2016 Plan              
Assumptions used to determine grant-date fair value              
Annual increase in authorized shares (as a percent) 4.00%            
Number of options or stock awards available for grant under the Plan   5,382,799   5,382,799      
2022 Plan              
Assumptions used to determine grant-date fair value              
Number of options or stock awards available for grant under the Plan             7,500,000
Options to purchase common stock              
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Non vested, Weighted Average Grant Date Fair Value              
Stock-based compensation expense   $ 1,253 $ 1,003 $ 3,723 $ 2,748    
Options to purchase common stock | Research and development              
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Non vested, Weighted Average Grant Date Fair Value              
Stock-based compensation expense   634 477 1,805 1,220    
Options to purchase common stock | General and administrative              
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Non vested, Weighted Average Grant Date Fair Value              
Stock-based compensation expense   619 $ 526 $ 1,918 $ 1,528    
Restricted stock units to purchase common stock              
Assumptions used to determine grant-date fair value              
Weighted average period for recognition of compensation cost       2 years 2 months 19 days      
Aggregate grant fair value       $ 6,777      
unrecognized compensation costs related to RSUs granted to employees   $ 4,463   $ 4,463      
Restricted stock units to purchase common stock | Executive Officer              
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Number of Shares [Roll Forward]              
Awarded       2,650,000 275,000    
Restricted stock units to purchase common stock | 2016 Plan              
Assumptions used to determine grant-date fair value              
Options unvested at end of period (in dollars per share)   $ 1.89   $ 1.89   $ 1.76  
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Number of Shares [Roll Forward]              
Outstanding at the beginning       935,606      
Awarded       2,650,000      
Outstanding at the end   3,585,606   3,585,606   935,606  
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Non vested, Weighted Average Grant Date Fair Value              
Outstanding at beginning( in dollars per share)       $ 1.76      
Awarded (in dollars per share)       1.93      
Outstanding at end(in dollars per share)   $ 1.89   $ 1.89   $ 1.76