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Commitments and Contingencies - Manufacturing, License and Other Agreements (Details)
$ in Thousands
3 Months Ended
Mar. 31, 2018
USD ($)
shares
TRX518 and DKN-01  
Commitments and Contingencies  
Noncancelable commitments $ 1,583
License and service agreements  
Commitments and Contingencies  
Accrued royalties $ 0
License and service agreements | Preferred Class A  
Commitments and Contingencies  
Issuance of stock in consideration for license (in shares) | shares 9,000,000
Licensing agreements  
Commitments and Contingencies  
Accrued royalties $ 0