Net Loss Per Share - Antidilutive (Details) - shares	12 Months Ended
	Dec. 31, 2018	Dec. 31, 2017
Securities excluded from computation of diluted net loss per share
Anti-dilutive securities excluded from calculation of diluted net loss per share	2,816,428	2,312,137
Options to purchase common stock
Securities excluded from computation of diluted net loss per share
Anti-dilutive securities excluded from calculation of diluted net loss per share	2,761,912	2,257,621
Warrants assumed from Macrocure
Securities excluded from computation of diluted net loss per share
Anti-dilutive securities excluded from calculation of diluted net loss per share	54,516	54,516