Commitments and Contingencies - Legal Proceedings (Details)	1 Months Ended	12 Months Ended
	Mar. 31, 2017 item	Dec. 31, 2017 company individual item
TRX518
Loss Contingencies
Number of notices of opposition filed		3
Number of major companies that filed notices of opposition | company		2
Number of individuals that filed notices of opposition | individual		1
TRX518 and Chemotherapeutic
Loss Contingencies
Number of notices of opposition filed	10