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Commitments and Contingencies - Manufacturing, License and Other Agreements (Details) - USD ($)
$ in Thousands
Dec. 30, 2016
Dec. 31, 2017
TRX518 and DKN-01    
Commitments and Contingencies    
Noncancelable commitments   $ 1,519
License and service agreements    
Commitments and Contingencies    
Accrued royalties   0
License and service agreements | Preferred Class A    
Commitments and Contingencies    
Issuance of stock in consideration for license (in shares) 9,000,000  
Licensing agreements    
Commitments and Contingencies    
Accrued royalties   $ 0