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Net Loss Per Share - Antidilutive (Details) - shares
12 Months Ended
Jan. 20, 2017
Dec. 31, 2017
Dec. 31, 2016
Securities excluded from computation of diluted net loss per share      
Anti-dilutive securities excluded from calculation of diluted net loss per share   2,312,137 3,326,736
Common Stock | Conversion of preferred stock into common stock      
Securities excluded from computation of diluted net loss per share      
Shares issued on conversion of preferred stock 3,174,523    
Common Stock | Conversion of notes payable - related party and accrued interest into common stock      
Securities excluded from computation of diluted net loss per share      
Shares issued on conversion of notes payable and related accrued interest 1,950,768    
Stock Options      
Securities excluded from computation of diluted net loss per share      
Anti-dilutive securities excluded from calculation of diluted net loss per share   2,257,621 53,228
Warrants assumed from Macrocure      
Securities excluded from computation of diluted net loss per share      
Anti-dilutive securities excluded from calculation of diluted net loss per share   54,516  
Convertible preferred stock and accrued dividends (as converted to common stock)      
Securities excluded from computation of diluted net loss per share      
Anti-dilutive securities excluded from calculation of diluted net loss per share     3,273,508