CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2017	Dec. 31, 2016
Operating expenses:
Research and development	$ 22,503	$ 23,292
General and administrative	9,849	4,012
Total operating expenses	32,352	27,304
Loss from operations	(32,352)	(27,304)
Interest income	170	2
Interest expense - related party	(121)	(1,233)
Australian research and development incentives	1,715	3,129
Foreign currency gains (loss)	759	(217)
Other expense, net	(55)	(9)
Loss before income taxes	(29,884)	(25,632)
Benefit from income taxes	157
Net loss	(29,727)	$ (25,632)
Accretion of preferred stock to redemption value	(244)
Net loss attributable to common stockholders	$ (29,971)
Net loss per share
Basic (in dollars per share)	$ (3.27)
Diluted (in dollars per share)	$ (3.31)
Weighted average common shares outstanding
Basic (in shares)	9,161,844
Diluted (in shares)	9,188,587