X0306 4 2018-02-26 0001572552 Asterias Biotherapeutics, Inc. AST 0001509725 Mulroy Michael H. C/O ASTERIAS BIOTHERAPEUTICS, INC. 6300 DUMBARTON CIRCLE FREMONT CA 94555 true true President and CEO Common Stock 2018-02-26 4 P 0 2255 2.2172 A 12188 D Stock Options (right to buy) 3.7 2027-06-26 Common Stock 800000 800000 D The shares were purchased in multiple trades at prices ranging from $2.175 to $2.225. The price reported above reflects the weighted average purchase price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. The shares of common stock reported herein were purchased via a 10b5-1 plan established by the Reporting Person on August 16, 2017, under which the Reporting Person is dedicating approximately 25 percent of his monthly after-tax salary to the purchase of Asterias common stock. Subject to Mr. Mulroy's continued employment with the Company, the stock options vest in equal monthly installments over 48 months commencing on July 31, 2017. The stock options are exercisable upon vesting. /s/ Michael H. Mulroy 2018-02-28