X0508 4 2025-08-18 0001509261 Rezolute, Inc. RZLT 0002083506 Karnawat Sunil Ratilal C/O REZOLUTE, INC. 275 SHORELINE DRIVE, SUITE 500 REDWOOD CITY CA 94065 true Chief Commercial Officer false Common Shares 2025-08-18 4 A 0 25000 0 A 27442 D Common Shares 8000 I Held in Imdividual Retirement Account Common Shares 1898 I Held in Heath Savings Account Employee Stock Option (Right to Buy) 6.55 2025-08-18 4 A 0 275000 0 A 2035-08-18 Common Shares 275000 275000 D Represents grant of restricted stock units which vest as follows: 1/4 on September 1, 2026; 1/4 on September 1, 2027; 1/4 on September 1, 2028; and 1/4 on September 1, 2029. The options shall vest and become exercisable as follows: One fourth (1/4) of such Options shall vest on the one-year anniversary of the grant date and one thirty-sixth (1/36) of the remaining Options shall vest on the same day of each month thereafter until the Option is 100% vested. The unvested portion of the Option will not be exercisable on or after the Reporting Person's termination of continuous service. /s/ Sunil Patilal Karnawat 2025-08-27