Note 7 - Stockholders' Equity (Deficit) - Restricted Stock Units Award Activity (Details) - Restricted Stock Units (RSUs) [Member] - $ / shares	9 Months Ended	12 Months Ended
Sep. 30, 2019	Sep. 30, 2018	Dec. 31, 2018	Dec. 31, 2017
Awards outstanding, Shares (in shares)	294,066	509	509
Awards outstanding, Weighted grant date fair value (in dollars per share)	$ 17.34	$ 2,377.80	$ 2,377.80
Awards outstanding, Weighted average remaining contractual term (Year)	2 years		3 years 36 days	2 years 317 days
Awarded, Shares (in shares)	764,151		297,753
Awarded, Weighted grant date fair value (in dollars per share)	$ 1.24	$ 15.80	$ 15	$ 1,144.10
Released, Shares (in shares)	(96,444)		(128)
Released, Weighted grant date fair value (in dollars per share)	$ 17.86		$ 2,739.70
Forfeited, Shares (in shares)	(20,205)		(4,068)
Forfeited, Weighted grant date fair value (in dollars per share)	$ 20.46		$ 59.70
Awards outstanding, Shares (in shares)	941,568		294,066	509
Awards outstanding, Weighted grant date fair value (in dollars per share)	$ 4.15		$ 17.34	$ 2,377.80

The number of equity-based payment instruments, excluding stock (or unit) options, that were forfeited during the reporting period.

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Weighted average fair value as of the grant date of equity-based award plans other than stock (unit) option plans that were not exercised or put into effect as a result of the occurrence of a terminating event.

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The number of grants made during the period on other than stock (or unit) option plans (for example, phantom stock or unit plan, stock or unit appreciation rights plan, performance target plan).

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The weighted average fair value at grant date for nonvested equity-based awards issued during the period on other than stock (or unit) option plans (for example, phantom stock or unit plan, stock or unit appreciation rights plan, performance target plan).

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The number of non-vested equity-based payment instruments, excluding stock (or unit) options, that validly exist and are outstanding as of the balance sheet date.

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Per share or unit weighted-average fair value of nonvested award under share-based payment arrangement. Excludes share and unit options.

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Weighted average remaining contractual term for equity-based awards excluding options, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.

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The number of equity-based payment instruments, excluding stock (or unit) options, that vested during the reporting period.

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The weighted average fair value as of grant date pertaining to an equity-based award plan other than a stock (or unit) option plan for which the grantee gained the right during the reporting period, by satisfying service and performance requirements, to receive or retain shares or units, other instruments, or cash in accordance with the terms of the arrangement.

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