Stock-Based Compensation, Stock Options (Details) - USD ($)	12 Months Ended
	Dec. 31, 2024	Dec. 31, 2023
Stock-Based Compensation Expense Items [Abstract]
Stock-based compensation expense	$ 478,000	$ 670,000
Minimum [Member]
Additional Disclosures [Abstract]
Award vesting period	1 year
Maximum [Member]
Additional Disclosures [Abstract]
Award vesting period	4 years
Selling, General and Administrative [Member]
Stock-Based Compensation Expense Items [Abstract]
Stock-based compensation expense	$ 464,000	630,000
Research and Development [Member]
Stock-Based Compensation Expense Items [Abstract]
Stock-based compensation expense	$ 14,000	$ 40,000
Stock Options [Member]
Stock Options Activity [Roll Forward]
Outstanding, beginning balance (in shares)	3,091	237
Granted (in shares)	1,264	3,590
Exercised (in shares)	0	0
Forfeited/expired (in shares)	(482)	(736)
Outstanding, ending balance (in shares)	3,873	3,091
Vested at the end of the year (in shares)	2,443	234
Weighted Average Exercise Price [Abstract]
Outstanding, beginning balance (in dollars per share)	$ 748.89	$ 8,738.32
Granted (in dollars per share)	24.14	223.66
Exercised (in dollars per share)	0	0
Forfeited/expired (in dollars per share)	557.34	743.18
Outstanding, ending balance (in dollars per share)	519.12	748.89
Vested at the end of the year (in dollars per share)	618.46	4,927.68
Weighted Average Fair Value [Abstract]
Outstanding, beginning balance (in dollars per share)	683.6	7,950.02
Granted (in dollars per share)	21.91	213.25
Exercised (in dollars per share)	0	0
Forfeited/expired (in dollars per share)	549.89	688.5
Outstanding, ending balance (in dollars per share)	473.83	683.6
Vested at the end of the year (in dollars per share)	$ 560.42	$ 4,416.23
Weighted Average Remaining Contractual Term [Abstract]
Options outstanding, weighted average remaining contractual life	8 years 5 months 19 days	9 years 2 months 4 days
Options vested, weighted average remaining contractual life	8 years 5 months 19 days	9 years 2 months 4 days
Aggregate Intrinsic Value [Abstract]
Aggregate intrinsic value for vested options	$ 0	$ 0
Fair value of options, vested	$ 498,455	$ 614,100,000,000
Weighted Average Assumptions used in Black-Scholes Option Pricing Model [Abstract]
Expected dividend yield	0.00%	0.00%
Risk-free interest rate	3.94%	4.16%
Expected volatility	138.70%	152.28%
Expected life	5 years 6 months 3 days	6 years 2 months 8 days
Additional Disclosures [Abstract]
Weighted-average fair value of options granted (in dollars per share)	$ 21.91	$ 213.25
Total unrecognized compensation costs related to non-vested stock option awards	$ 500,000
Unrecognized compensation costs related to non-vested stock option awards, recognition life	2 years 3 months 14 days