Stockholders' Equity (Details) $ / shares in Units, $ in Thousands, $ in Millions												12 Months Ended
	Nov. 05, 2024 USD ($) $ / shares shares	Aug. 23, 2024 USD ($) $ / shares shares	Jul. 25, 2024 USD ($) $ / shares shares	Jun. 26, 2024	Jun. 06, 2024	Apr. 30, 2024 USD ($) Warrant $ / shares shares	Oct. 17, 2023 USD ($) $ / shares shares	Oct. 17, 2023 AUD ($)	Oct. 12, 2023 shares $ / shares	Mar. 12, 2019	Nov. 27, 2017 USD ($)	Dec. 31, 2024 USD ($) $ / shares shares	Dec. 31, 2023 USD ($) $ / shares shares	Aug. 30, 2024 $ / shares	Aug. 13, 2024 $ / shares shares
Class of Stock Disclosures [Abstract]
Preferred stock, shares outstanding (in shares)												0	0
Warrants to purchase shares of common stock (in shares)	1,832,517
Offering expense | $	$ 1,400
Common stock, par value (in dollars per share) | $ / shares												$ 0.0001	$ 0.0001
Exercise price of warrants (in dollars per share) | $ / shares	$ 2.1
Converted warrant | $												$ 4,217	$ 7,623
Preferred stock, par value (in dollars per share) | $ / shares												$ 0.0001	$ 0.0001
Gross proceeds prior to deducting inducement agent fees and estimated offering expenses | $	$ 3,800
Common stock warrant liability | $												$ 468	$ 2,843
Reverse stock split				0.029
Minimum [Member]
Class of Stock Disclosures [Abstract]
Reverse stock split					0.20
Maximum [Member]
Class of Stock Disclosures [Abstract]
Reverse stock split					0.014
At-the-Market Program [Member]
Class of Stock Disclosures [Abstract]
Issuance of common stock, net (in shares)													18,781
Gross proceeds from public stock offering | $													$ 2,300
Net proceeds from public stock offering | $													$ 2,100
Aggregate cash fee paid to underwriter or placement agent												3.00%
April 2024 Offering [Member]
Class of Stock Disclosures [Abstract]
Issuance of common stock, net (in shares)						240,571
Warrants to purchase shares of common stock (in shares)						3,214,288									2,498,331
Exercise price of warrants (in dollars per share) | $ / shares						$ 2.1						$ 2.23		$ 2.1	$ 2.49
No of warrants converted to equity (in shares)												2,737,816
Converted warrant | $												$ 5,600
Gross proceeds before deducting the placement agent fees and other offering expenses | $						$ 2,700
Issuance of common stock for pre-funded warrants (in shares)						80,854
Common stock offering price per share (in dollars per share) | $ / shares						$ 8.4
Number of warrants included in each unit | Warrant						1
Warrants to purchase common shares (in shares)						1.50						2,737,816
Warrant expiry period												5 years
August 2024 Offering [Member]
Class of Stock Disclosures [Abstract]
Warrants to purchase shares of common stock (in shares)		14,501
Exercise price of warrants (in dollars per share) | $ / shares		$ 3.04425
Gross proceeds before deducting the placement agent fees and other offering expenses | $		$ 631,000
Warrants to Purchase Common Stock [Member]
Class of Stock Disclosures [Abstract]
Warrants to purchase shares of common stock (in shares)	54,976
Warrants to purchase common shares (in shares)						1
Number of trading days												5 days
Floor price per share (in dollars per share) | $ / shares												$ 2.1
Series I Warrants and Series II Warrants [Member]
Class of Stock Disclosures [Abstract]
Warrants to purchase shares of common stock (in shares)	3,665,034
Series I Warrants [Member]
Class of Stock Disclosures [Abstract]
Exercise price of warrants (in dollars per share) | $ / shares	$ 1.94
Warrant expiry period												5 years
Warrants exercisable period												6 months
Series II Warrants [Member]
Class of Stock Disclosures [Abstract]
Exercise price of warrants (in dollars per share) | $ / shares	$ 1.94
Warrant expiry period												2 years
Warrants exercisable period												6 months
Supply Agreement [Member] | Maximum [Member]
Class of Stock Disclosures [Abstract]
Period for ultrafiltration services												10 years
Securities Purchase Agreement [Member]
Class of Stock Disclosures [Abstract]
Common stock, par value (in dollars per share) | $ / shares		$ 0.0001
Net proceeds after deducting placement agent fees and commissions and offering expenses | $			$ 1,500
Securities Purchase Agreement [Member] | July 2024 Offering [Member]
Class of Stock Disclosures [Abstract]
Issuance of common stock, net (in shares)			469,340
Exercise price of warrants (in dollars per share) | $ / shares			$ 3.99
Gross proceeds before deducting placement agent fees and commissions and offering expenses | $			$ 2,000
Common stock offering price per share (in dollars per share) | $ / shares		$ 1.845	$ 4.24
Warrants to purchase common shares (in shares)			938,680
Warrant expiry period												5 years
Securities Purchase Agreement [Member] | August 2024 Offering [Member]
Class of Stock Disclosures [Abstract]
Issuance of common stock, net (in shares)		483,351
Warrants to purchase shares of common stock (in shares)		483,351
Exercise price of warrants (in dollars per share) | $ / shares		$ 1.72
Series F Convertible Preferred Stock [Member]
Class of Stock Disclosures [Abstract]
Number of consecutive trading days considered for expiration												20 days
Number of consecutive trading days												30 days
Percentage of volume weighted average price of common stock											300.00%
Trading volume for each trading day | $											$ 7,000
Conversion price (in dollars per share) | $ / shares		$ 542.01
Preferred stock, shares outstanding (in shares)												127	127
Preferred stock, par value (in dollars per share) | $ / shares												$ 0.0001	$ 0.0001
Series F Convertible Preferred Stock [Member] | Minimum [Member]
Class of Stock Disclosures [Abstract]
Aggregate cash fee paid to underwriter or placement agent										8.00%
Series F Convertible Preferred Stock [Member] | Maximum [Member]
Class of Stock Disclosures [Abstract]
Aggregate cash fee paid to underwriter or placement agent										7.00%
Series J Convertible Preferred Stock [Member] | October 2023 Offering [Member]
Class of Stock Disclosures [Abstract]
Issuance of common stock, net (in shares)									150,000
Warrants to purchase shares of common stock (in shares)									0.5
Number of shares in one unit (in shares)									1
Original issue discount percentage									40.00%
Additional shares issuable upon declaration of dividends (in shares)									362,933
Common stock offering price per share (in dollars per share) | $ / shares									$ 15
Preferred stock, par value (in dollars per share) | $ / shares									$ 0.0001
Number of warrants included in each unit									1
Common Stock [Member]
Class of Stock Disclosures [Abstract]
Issuance of common stock, net (in shares)												1,274,108	18,781
Converted warrant | $												$ 0	$ 0
Common Stock [Member] | Series J Convertible Preferred Stock [Member] | October 2023 Offering [Member]
Class of Stock Disclosures [Abstract]
Common stock, par value (in dollars per share) | $ / shares									$ 0.0001
Warrants [Member]
Class of Stock Disclosures [Abstract]
Common stock warrant liability | $							$ 7,800
Warrants [Member] | October 2023 Offering [Member]
Class of Stock Disclosures [Abstract]
Gross proceeds before deducting placement agent fees and commissions and offering expenses | $							2,250
Net proceeds after deducting placement agent fees and commissions and offering expenses | $							$ 1,500
Financing expense | $								$ 2.7
Warrants [Member] | Series J Convertible Preferred Stock [Member] | October 2023 Offering [Member]
Class of Stock Disclosures [Abstract]
Warrants to purchase shares of common stock (in shares)							0.5
Exercise price of warrants (in dollars per share) | $ / shares							$ 262.5
Warrants term												3 years