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Nature of Business and Basis of Presentation, Loss Per Share (Details) - USD ($)
$ / shares in Units, $ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2019
Jun. 30, 2019
Mar. 31, 2019
Sep. 30, 2018
Jun. 30, 2018
Mar. 31, 2018
Sep. 30, 2019
Sep. 30, 2018
Dec. 31, 2018
Potential shares of common stock that are not included in the calculation of diluted net loss per share [Abstract]                  
Potential shares of common stock that are not included in the calculation of diluted net loss per share (in shares)             5,865,628 767,439  
Reported net loss with reported net loss per share [Abstract]                  
Net loss $ (4,509) $ (4,430) $ (4,727) $ (4,241) $ (4,181) $ (4,354) $ (13,666) $ (12,776)  
Deemed dividend to preferred shareholders (see Note 4) 0           (4,509)    
Net loss after deemed dividend $ (4,509)           $ (18,175)    
Weighted average shares outstanding (in shares) 2,646,000     499,000     1,915,000 369,000  
Basic and diluted loss per share (in dollars per share) $ (1.70)     $ (8.50)     $ (9.49) $ (34.59)  
New Accounting Pronouncement [Abstract]                  
Operating lease right-of-use asset $ 487           $ 487   $ 0
Operating lease liability $ 490           $ 490    
Warrants to Purchase Common Stock [Member]                  
Potential shares of common stock that are not included in the calculation of diluted net loss per share [Abstract]                  
Potential shares of common stock that are not included in the calculation of diluted net loss per share (in shares)             5,430,721 608,787  
Series F Convertible Preferred Stock [Member]                  
Potential shares of common stock that are not included in the calculation of diluted net loss per share [Abstract]                  
Potential shares of common stock that are not included in the calculation of diluted net loss per share (in shares)             102,185 19,210  
Stock Options [Member]                  
Potential shares of common stock that are not included in the calculation of diluted net loss per share [Abstract]                  
Potential shares of common stock that are not included in the calculation of diluted net loss per share (in shares)             332,722 139,439  
Restricted Stock Units [Member]                  
Potential shares of common stock that are not included in the calculation of diluted net loss per share [Abstract]                  
Potential shares of common stock that are not included in the calculation of diluted net loss per share (in shares)             0 3  
ASU 2016-02 [Member] | Adjustments Due to Adoption of ASU 2016-02 [Member]                  
New Accounting Pronouncement [Abstract]                  
Operating lease right-of-use asset                 600
Operating lease liability                 $ 600