Income taxes - Narrative (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2025	Dec. 31, 2024	Dec. 31, 2023
Income Taxes [Line Items]
Income taxes paid, net	$ 22,376	$ 25,018	$ 19,173
Increase (decrease) in valuation allowance	24,000
Unrecognized tax benefits that would affect effective tax rate	370,200
Effective tax rate impact	219,400
Remaining unrecognized tax benefits	150,800
Federal
Income Taxes [Line Items]
Net operating loss carryforwards	2,160,600
Federal | Research Tax Credits
Income Taxes [Line Items]
Tax credit carryforwards	711,400
California
Income Taxes [Line Items]
Net operating loss carryforwards	554,300
California | Research Tax Credits
Income Taxes [Line Items]
Tax credit carryforwards	490,000
All other state and local
Income Taxes [Line Items]
Net operating loss carryforwards	956,400
All other state and local | Research Tax Credits
Income Taxes [Line Items]
Tax credit carryforwards	2,000
Foreign | Research Tax Credits
Income Taxes [Line Items]
Tax credit carryforwards	3,400
Ireland
Income Taxes [Line Items]
Net operating loss carryforwards	198,200
All other foreign
Income Taxes [Line Items]
Net operating loss carryforwards	$ 6,700