144 0001506045 XXXXXXXX LIVE 0000879407 Arrowhead 001-38042 177 East Colorado Blvd Suite 700 Pasadena CA 91105 6266964702 Mauro Ferrari Director Common Merrill Lynch

75 Rockefeller Plz Flr 2 New York NY 10019

7530 527070.05 135809558 12/26/2025 NASDAQ Common 12/18/2024 Compensation Issuer N 16733 12/18/2024 Compensation N Mauro Ferrari

177 E Colorado Blvd Suite 700 Pasadena CA 91105

Common 11/28/2025 8750 493062.5 12/26/2025 09/25/2025 Mauro Ferrari