X0306 4 2020-10-09 0001280784 Hercules Capital, Inc. HTGC 0001505910 Bluestein Scott C/O HERCULES CAPITAL, INC. 31 ST. JAMES AVENUE, SUITE 790 BOSTON MA 02116 1 Chief Executive Officer Common Stock 2020-10-09 4 F 0 3402 12.04 D 674759 D Restricted Stock Units 2020-10-09 4 F 0 243 12.04 D 443617 D Represents shares of common stock withheld to pay taxes applicable to the vesting of restricted stock on October 9, 2020. Represents restricted stock units withheld to pay taxes applicable to the vesting of restricted stock units and dividend equivalent shares on October 9, 2020. /s/ /Melanie Grace, Attorney-in-Fact for Scott Bluestein 2020-10-14