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Stockholders' Equity (Assumptions Used to Estimate Fair Value of Stock Options and Performance Stock and Employee Stock Purchase Plan) (Details)
3 Months Ended
Mar. 31, 2023
Mar. 31, 2022
Stock options    
Weighted average assumptions    
Risk-free interest rate 3.60% 1.70%
Volatility 96.50% 95.70%
Dividend yield 0.00% 0.00%
Expected term (years) 6 years 1 month 6 days 6 years 1 month 6 days
Employee stock purchase plan shares    
Weighted average assumptions    
Risk-free interest rate 4.00% 0.30%
Volatility 104.40% 97.80%
Dividend yield 0.00% 0.00%
Expected term (years) 6 months 6 months