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Stockholders' Equity - Assumptions Used to Estimate Fair Value of Stock Options and Performance Stock and Employee Stock Purchase Plan (Details)
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Stock options    
Weighted average assumptions    
Risk-free interest rate 2.00% 1.00%
Volatility 96.10% 95.80%
Dividend yield 0.00% 0.00%
Expected term (years) 6 years 1 month 6 days 6 years 1 month 6 days
Performance stock options    
Weighted average assumptions    
Risk-free interest rate 0.00% 1.00%
Volatility 0.00% 95.70%
Dividend yield 0.00% 0.00%
Expected term (years) 0 years 6 years 1 month 6 days
2022 Employee Stock Purchase Plan    
Weighted average assumptions    
Risk-free interest rate 1.60% 0.10%
Volatility 104.70% 101.20%
Dividend yield 0.00% 0.00%
Expected term (years) 6 months 6 months