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Collaborations (Details)
1 Months Ended 3 Months Ended 12 Months Ended
Oct. 31, 2020
USD ($)
Sep. 30, 2020
USD ($)
Aug. 31, 2020
USD ($)
Nov. 30, 2018
USD ($)
Feb. 28, 2014
USD ($)
Jun. 30, 2013
USD ($)
Jul. 31, 2012
target
Mar. 31, 2022
USD ($)
Mar. 31, 2021
USD ($)
Dec. 31, 2019
USD ($)
Nov. 30, 2020
USD ($)
Revenue under collaborations                      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                      
Total revenues               $ 0 $ 0    
Sanofi                      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                      
Number of collaborative areas granted | target             4        
Initial upfront option payment $ 4,000,000 $ 1,000,000 $ 1,000,000                
Potential revenue through milestone payments       $ 6,800,000              
Agreement period       24 months              
Upfront payment non-creditable portion recognized                   $ 6,800,000  
Enrollment Milestone     10,000,000                
Contract with customer, asset                     $ 5,000,000
Development milestone not achievable               $ 25,000,000      
Sanofi | Minimum | United States                      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                      
Royalties based on percentage of net sales               10.00%      
Sanofi | Minimum | Outside of the United States                      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                      
Royalties based on percentage of net sales               10.00%      
Sanofi | Maximum | United States                      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                      
Royalties based on percentage of net sales               20.00%      
Sanofi | Maximum | Outside of the United States                      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                      
Royalties based on percentage of net sales               20.00%      
Sanofi | Development Commercialization And License Agreement                      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                      
Deferred revenue creditable against future milestones         $ 1,250,000     $ 1,250,000      
Initial upfront option payment           $ 2,500,000          
Sanofi | Proof-of-Concept Trial                      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                      
Potential revenue through milestone payments               38,800,000      
Sanofi | Clinical                      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                      
Potential revenue through milestone payments               25,000,000      
Sanofi | Regulatory and Commercialization Milestones                      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                      
Potential revenue through milestone payments               $ 130,000,000      
Sanofi | Development Milestones                      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                      
Potential revenue through milestone payments     25,000,000 $ 40,000,000              
Sanofi | Enrollment Milestone                      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                      
Potential revenue through milestone payments       $ 10,000,000              
Sanofi | Materials Sold                      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                      
Potential revenue through milestone payments     4,000,000                
Sanofi | Achievement of Enrollment Milestone                      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                      
Potential revenue through milestone payments     $ 5,000,000