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Stockholders' Equity (Assumptions Used to Estimate Fair Value of Stock Options and Performance Stock and Employee Stock Purchase Plan) (Details)
3 Months Ended 9 Months Ended
Sep. 30, 2021
Sep. 30, 2020
Sep. 30, 2021
Sep. 30, 2020
Stock options        
Weighted average assumptions        
Risk-free interest rate 0.90% 0.40% 1.00% 1.10%
Volatility 96.00% 95.30% 95.80% 95.40%
Dividend yield 0.00% 0.00% 0.00% 0.00%
Expected term (years) 6 years 1 month 6 days 6 years 1 month 6 days 6 years 1 month 6 days 6 years 1 month 6 days
Performance stock options        
Weighted average assumptions        
Risk-free interest rate 0.00% 0.00% 1.00% 1.40%
Volatility 0.00% 0.00% 95.70% 95.40%
Dividend yield 0.00% 0.00% 0.00% 0.00%
Expected term (years) 0 months 0 months 6 years 1 month 6 days 6 years 1 month 6 days
Employee stock purchase plan shares        
Weighted average assumptions        
Risk-free interest rate 0.10% 0.30% 0.10% 0.70%
Volatility 103.10% 94.90% 104.40% 98.20%
Dividend yield 0.00% 0.00% 0.00% 0.00%
Expected term (years) 6 months 6 months 6 months 6 months