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Convertible Note Payable	12 Months Ended
Convertible Note Payable	Dec. 31, 2017
Debt Disclosure [Abstract]
Convertible Note Payable	Convertible Note Payable In October 2012, in conjunction with our initial public offering, we issued a convertible note to GSK LLC (the "GSK Note") in the principal amount of $5.4 million, with a maturity date of October 9, 2015. On January 29, 2015, the principal amount outstanding under the GSK Note of $5.4 million was converted into 1,356,738 shares of our common stock at a conversion price of $4.00 per share. We recorded a loss from the change in valuation of the convertible note payable of $1.8 million upon its conversion.