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Stockholders' Equity (Assumptions Used to Estimate Fair Value of Stock Options and Performance Stock and Employee Stock Purchase Plan) (Detail)
3 Months Ended 6 Months Ended
Jun. 30, 2016
Jun. 30, 2015
Jun. 30, 2016
Jun. 30, 2015
Employee Stock Purchase Plan        
Weighted average assumptions        
Risk-free interest rate 0.50% 0.10% 0.40% 0.10%
Volatility 82.60% 76.90% 81.00% 74.90%
Dividend yield 0.00% 0.00% 0.00% 0.00%
Expected term (years) 6 months 6 months 6 months 6 months
Stock options        
Weighted average assumptions        
Risk-free interest rate 1.50% 1.80% 1.40% 1.80%
Volatility 79.10% 79.10% 79.70% 78.80%
Dividend yield 0.00% 0.00% 0.00% 0.00%
Expected term (years) 5 years 9 months 18 days 6 years 1 month 6 days 5 years 10 months 24 days 6 years 1 month 6 days
Performance stock options        
Weighted average assumptions        
Risk-free interest rate 0.40% 0.00% 1.40% 1.80%
Volatility 78.50% 0.00% 79.30% 76.40%
Dividend yield 0.00% 0.00% 0.00% 0.00%
Expected term (years) 5 years 6 months 0 years 6 years 6 years