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Condensed Statements of Cash Flows - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2016
Mar. 31, 2015
Operating activities    
Net loss $ (21,207) $ (14,487)
Adjustments to reconcile net loss to net cash used in operating activities    
Depreciation and amortization expense 419 394
Loss from valuation of convertible note payable 0 1,811
Stock-based compensation 3,749 3,103
Amortization of premium on investments, net 198 425
Loss on disposal of long-term assets 0 50
Change in operating assets and liabilities:    
Contracts and other receivables 9,959 (2,469)
Prepaid expenses (1,113) (148)
Other assets 338 226
Accounts payable 906 471
Accrued liabilities (596) 899
Accrued compensation (1,181) (1,059)
Deferred revenue (489) (389)
Deferred rent and other liabilities 87 (79)
Net cash used in operating activities (8,930) (11,252)
Investing activities    
Purchases of short-term investments (20,475) (37,157)
Sales and maturities of short-term investments 32,572 30,010
Purchases of property and equipment (395) (236)
Acquisition of intangibles (11) (7)
Net cash provided by (used in) investing activities 11,691 (7,390)
Financing activities    
Proceeds from issuance of common stock, net 363 257
Proceeds from exercise of common stock options 206 695
Principal payments on other long-term obligations (41) (37)
Net cash provided by financing activities 528 915
Net increase (decrease) in cash and cash equivalents 3,289 (17,727)
Cash and cash equivalents at beginning of period 15,960 37,327
Cash and cash equivalents at end of period 19,249 19,600
Supplemental disclosure of cash flow information    
Net changes in restricted cash (338) 0
Interest paid (5) (8)
Income taxes paid (1) (1)
Supplemental disclosure of non-cash investing and financing activities    
Allowance for tenant improvements 5,470 0
Amounts accrued for property and equipment $ 86 $ 14