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Convertible Note Payable - Additional Information (Detail) (USD $)
1 Months Ended
Oct. 31, 2012
Sep. 30, 2014
Dec. 31, 2013
Debt Instrument [Line Items]      
Conversion date Oct. 09, 2015    
Conversion price per shares   $ 4.00  
Convertible note payable, at fair value   $ 10,665,000 $ 11,279,000
Convertible Debt | GSK
     
Debt Instrument [Line Items]      
Convertible notes issued $ 5,400,000