<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0508</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2023-08-20</periodOfReport>

    <issuer>
        <issuerCik>0001504167</issuerCik>
        <issuerName>Timber Pharmaceuticals, Inc.</issuerName>
        <issuerTradingSymbol>TMBR</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001842511</rptOwnerCik>
            <rptOwnerName>Mendelsohn Alan</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O TIMBER PHARMACEUTICALS, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>3 MOUNTAINVIEW RD, SUITE 100</rptOwnerStreet2>
            <rptOwnerCity>WARREN</rptOwnerCity>
            <rptOwnerState>NJ</rptOwnerState>
            <rptOwnerZipCode>07059</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isOfficer>1</isOfficer>
            <officerTitle>EVP &amp; CMO</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <aff10b5One>0</aff10b5One>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock, par value $0.001 per share</value>
            </securityTitle>
            <transactionDate>
                <value>2023-08-20</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>A</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>35193</value>
                    <footnoteId id="F1"/>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>35393</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock, par value $0.001 per share</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>39</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>By spouse</value>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">On August 20, 2023, the Reporting Person was granted 35,193 restricted stock units (&quot;RSUs&quot;), which will be settled in shares of common stock, par value $0.001. 25% of the RSUs vest on August 20, 2024, and the remaining RSUs vest in 36 equal monthly installments beginning on September 20, 2024, as long as the Reporting Person remains in continuous service with the Issuer through each vesting date; provided, however, that the RSUs will vest in full in the event that a &quot;Change in Control&quot; (as defined in the Issuer's 2020 Omnibus Incentive Plan) occurs while the Reporting Person remains in continuous service with the Issuer.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Joseph Lucchese, Power of Attorney</signatureName>
        <signatureDate>2023-08-22</signatureDate>
    </ownerSignature>
</ownershipDocument>
