0001209191-18-059990.txt : 20181127 0001209191-18-059990.hdr.sgml : 20181127 20181127162052 ACCESSION NUMBER: 0001209191-18-059990 CONFORMED SUBMISSION TYPE: 4 PUBLIC DOCUMENT COUNT: 1 CONFORMED PERIOD OF REPORT: 20181126 FILED AS OF DATE: 20181127 DATE AS OF CHANGE: 20181127 REPORTING-OWNER: OWNER DATA: COMPANY CONFORMED NAME: Shacham Sharon CENTRAL INDEX KEY: 0001588438 FILING VALUES: FORM TYPE: 4 SEC ACT: 1934 Act SEC FILE NUMBER: 001-36167 FILM NUMBER: 181203255 MAIL ADDRESS: STREET 1: C/O KARYOPHARM THERAPEUTICS INC. STREET 2: 85 WELLS AVENUE, SECOND FLOOR CITY: NEWTON STATE: MA ZIP: 02459 ISSUER: COMPANY DATA: COMPANY CONFORMED NAME: Karyopharm Therapeutics Inc. CENTRAL INDEX KEY: 0001503802 STANDARD INDUSTRIAL CLASSIFICATION: PHARMACEUTICAL PREPARATIONS [2834] IRS NUMBER: 263931704 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 BUSINESS ADDRESS: STREET 1: 85 WELLS AVENUE STREET 2: SECOND FLOOR CITY: NEWTON STATE: MA ZIP: 02459 BUSINESS PHONE: 617-658-0600 MAIL ADDRESS: STREET 1: 85 WELLS AVENUE STREET 2: SECOND FLOOR CITY: NEWTON STATE: MA ZIP: 02459 4 1 doc4.xml FORM 4 SUBMISSION X0306 4 2018-11-26 0 0001503802 Karyopharm Therapeutics Inc. KPTI 0001588438 Shacham Sharon C/O KARYOPHARM THERAPEUTICS INC. 85 WELLS AVENUE NEWTON MA 02459 0 1 0 0 President & CSO Common Stock 2018-11-26 4 M 0 9600 4.752 A 521743 I By Spouse Common Stock 2018-11-26 4 S 0 9600 11.00 D 512143 I By Spouse Common Stock 713510 D Common Stock 47309 I By GRAT Common Stock 47309 I By Spouse's GRAT Stock Option (right to buy) 4.752 2018-11-26 4 M 0 9600 0.00 D 2023-09-02 Common Stock 9600 436061 I By Spouse These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the spouse of the reporting person. These shares are held by the Sharon Shacham 2016 Qualified Annuity Interest Trust. These shares are held by the Michael G. Kauffman 2016 Qualified Annuity Interest Trust. This option, representing a right to purchase a specified number of shares, vested as to 25% of the shares on September 3, 2014, and the remaining 75% vested in 36 equal monthly installments thereafter. /s/ Christopher B. Primiano, Attorney-in-Fact for Sharon Shacham 2018-11-27