0001209191-18-045810.txt : 20180808 0001209191-18-045810.hdr.sgml : 20180808 20180808160432 ACCESSION NUMBER: 0001209191-18-045810 CONFORMED SUBMISSION TYPE: 4 PUBLIC DOCUMENT COUNT: 1 CONFORMED PERIOD OF REPORT: 20180807 FILED AS OF DATE: 20180808 DATE AS OF CHANGE: 20180808 REPORTING-OWNER: OWNER DATA: COMPANY CONFORMED NAME: Shacham Sharon CENTRAL INDEX KEY: 0001588438 FILING VALUES: FORM TYPE: 4 SEC ACT: 1934 Act SEC FILE NUMBER: 001-36167 FILM NUMBER: 181001324 MAIL ADDRESS: STREET 1: C/O KARYOPHARM THERAPEUTICS INC. STREET 2: 85 WELLS AVENUE, SECOND FLOOR CITY: NEWTON STATE: MA ZIP: 02459 ISSUER: COMPANY DATA: COMPANY CONFORMED NAME: Karyopharm Therapeutics Inc. CENTRAL INDEX KEY: 0001503802 STANDARD INDUSTRIAL CLASSIFICATION: PHARMACEUTICAL PREPARATIONS [2834] IRS NUMBER: 263931704 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 BUSINESS ADDRESS: STREET 1: 85 WELLS AVENUE STREET 2: SECOND FLOOR CITY: NEWTON STATE: MA ZIP: 02459 BUSINESS PHONE: 617-658-0600 MAIL ADDRESS: STREET 1: 85 WELLS AVENUE STREET 2: SECOND FLOOR CITY: NEWTON STATE: MA ZIP: 02459 4 1 doc4.xml FORM 4 SUBMISSION X0306 4 2018-08-07 0 0001503802 Karyopharm Therapeutics Inc. KPTI 0001588438 Shacham Sharon C/O KARYOPHARM THERAPEUTICS INC. 85 WELLS AVENUE NEWTON MA 02459 0 1 0 0 President & CSO Common Stock 2018-08-07 4 M 0 12500 0.033 A 726010 D Common Stock 2018-08-07 4 S 0 12500 18.0445 D 713510 D Common Stock 512143 I By Spouse Common Stock 47309 I By GRAT Common Stock 47309 I By Spouse's GRAT Stock Option (right to buy) 0.033 2018-08-07 4 M 0 12500 0.00 D 2020-10-21 Common Stock 12500 14264 D These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. Represents the weighted average sale price. These shares were sold in multiple transactions at prices ranging from $17.60 to $18.85, inclusive. The reporting person undertakes to provide upon request by the U.S. Securities and Exchange Commission staff, the issuer or a security holder of the issuer, full information regarding the number of shares sold at each separate price. These shares are held by the Sharon Shacham 2016 Qualified Annuity Interest Trust. These shares are held by the Michael G. Kauffman 2016 Qualified Annuity Interest Trust. This option, representing a right to purchase a specified number of shares, vested as to 25% of the shares on October 22, 2011, and the remaining 75% vested in 36 equal monthly installments thereafter. /s/ Christopher B. Primiano, Attorney-in-Fact for Sharon Shacham 2018-08-08