Consolidated Statements of Operations - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2025	Dec. 31, 2024	Dec. 31, 2023
Segment revenues:
Revenue from contract with customer, license and other revenue	$ 146,067	$ 145,237	$ 146,033
Operating expenses:
Research and development	125,617	143,232	138,750
Selling, general and administrative	105,208	115,441	131,881
Total operating expenses	236,774	264,680	275,573
Loss from operations	(90,707)	(119,443)	(129,540)
Other income (expense):
Interest income	2,773	7,400	10,943
Interest expense	(45,849)	(37,422)	(23,823)
(Loss) gain on extinguishment of debt	(62,365)	44,702	0
Other income (expense), net	152	28,398	(356)
Total other (expense) income, net	(105,289)	43,078	(13,236)
Loss before income taxes	(195,996)	(76,365)	(142,776)
Income tax provision	(43)	(57)	(323)
Net loss	$ (196,039)	$ (76,422)	$ (143,099)
Basic net loss per share	$ (17.93)	$ (9.41)	$ (18.79)
Diluted net loss per share (Note 2)	$ (17.93)	$ (14)	$ (18.79)
Weighted-average number of common shares outstanding used to compute basic net loss per share	10,935	8,125	7,616
Weighted-average number of common shares outstanding used to compute diluted net loss per share	10,935	8,455	7,616
Product [Member]
Segment revenues:
Revenue from contract with customer, license and other revenue	$ 114,857	$ 112,806	$ 112,011
Operating expenses:
Cost of sales	5,949	6,007	4,942
License and Other [Member]
Segment revenues:
Revenue from contract with customer, license and other revenue	$ 31,210	$ 32,431	$ 34,022