<SEC-DOCUMENT>0001179110-14-011663-index.html : 20140709
<SEC-HEADER>0001179110-14-011663.hdr.sgml : 20140709
<ACCEPTANCE-DATETIME>20140709192534
ACCESSION NUMBER:		0001179110-14-011663
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20140708
FILED AS OF DATE:		20140709
DATE AS OF CHANGE:		20140709

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Karyopharm Therapeutics Inc.
		CENTRAL INDEX KEY:			0001503802
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				263931704
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		2 MERCER ROAD
		CITY:			NATICK
		STATE:			MA
		ZIP:			01760
		BUSINESS PHONE:		508-975-4820

	MAIL ADDRESS:	
		STREET 1:		2 MERCER ROAD
		CITY:			NATICK
		STATE:			MA
		ZIP:			01760

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			PAKIANATHAN DEEPIKA
		CENTRAL INDEX KEY:			0001270734

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-36167
		FILM NUMBER:		14968118

	MAIL ADDRESS:	
		STREET 1:		3000 SAND HILL RD, BLDG 1, STE 135
		STREET 2:		C/O DELPHI VENTURES
		CITY:			MENLO PARK
		STATE:			CA
		ZIP:			94025
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>edgar.xml
<DESCRIPTION>FORM 4 -
<TEXT>
Document 1 - file: edgar.html

Document 1 - RAW XML: edgar.xml

</DOCUMENT>
</SEC-DOCUMENT>