Property and Equipment, Net - Schedule of Property and Equipment, Net (Detail) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2023	Dec. 31, 2022
Property, Plant and Equipment [Line Items]
Property and equipment, gross	$ 7,171	$ 7,784
Less accumulated depreciation and amortization	(6,565)	(6,645)
Property and equipment, net	$ 606	1,139
Laboratory Equipment [Member]
Property, Plant and Equipment [Line Items]
Estimated useful life	4 years
Property and equipment, gross	$ 830	870
Furniture and Fixtures [Member]
Property, Plant and Equipment [Line Items]
Estimated useful life	5 years
Property and equipment, gross	$ 654	654
Office Equipment [Member]
Property, Plant and Equipment [Line Items]
Estimated useful life	3 years
Property and equipment, gross	$ 809	809
Leasehold Improvements [Member]
Property, Plant and Equipment [Line Items]
Estimated useful life	Lesser of useful life or lease term
Property and equipment, gross	$ 4,878	$ 5,451