Consolidated Statements of Stockholders' Equity (Deficit) - USD ($) $ in Thousands	Total	Common Stock [Member]	Additional Paid-In Capital [Member]	Accumulated Other Comprehensive (loss) Income [Member]	Accumulated Deficit [Member]
Beginning balance at Dec. 31, 2020	$ 50,546	$ 7	$ 1,119,632	$ 518	$ (1,069,611)
Beginning balance,Shares at Dec. 31, 2020		73,923,000
Vesting of restricted stock (in shares)		480,000
Exercise of stock options and shares issued under the employee stock purchase plan	3,745		3,745
Exercise of stock options and shares issued under the employee stock purchase plan, (shares)		555,000
Stock-based compensation expense	29,783		29,783
Issuance of common stock for asset purchase	1,355		1,355
Issuance of common stock for asset purchase, Shares		150,000
Issuance of common stock, net of issuance costs	9,903	$ 1	9,902
Issuance of common stock, net of issuance costs (in Shares)		638,000
Cumulative effect adjustment for adoption of new accounting guidance	(50,590)		(65,641)		15,051
Unrealized gain loss on investments	(286)			(286)
Foreign currency cumulative translation adjustment	(41)			(41)
Net loss	(124,088)				(124,088)
Ending balance at Dec. 31, 2021	(79,673)	$ 8	1,098,776	191	(1,178,648)
Ending balance,Shares at Dec. 31, 2021		75,746,000
Vesting of restricted stock (in shares)		957,000
Exercise of stock options and shares issued under the employee stock purchase plan	3,977		3,977
Exercise of stock options and shares issued under the employee stock purchase plan, (shares)		726,000
Stock-based compensation expense	35,399		35,399
Issuance of common stock, net of issuance costs	189,761	$ 4	189,757
Issuance of common stock, net of issuance costs (in Shares)		35,784,000
Unrealized gain loss on investments	(341)			(341)
Foreign currency cumulative translation adjustment	(488)			(488)
Net loss	(165,291)				(165,291)
Ending balance at Dec. 31, 2022	(16,656)	$ 12	1,327,909	(638)	(1,343,939)
Ending balance,Shares at Dec. 31, 2022		113,213,000
Vesting of restricted stock (in shares)		1,054,000
Exercise of stock options and shares issued under the employee stock purchase plan	1,124		1,124
Exercise of stock options and shares issued under the employee stock purchase plan, (shares)		648,000
Stock-based compensation expense	21,709		21,709
Issuance of common stock warrants	239		239
Unrealized gain loss on investments	278			278
Foreign currency cumulative translation adjustment	199			199
Net loss	(143,099)				(143,099)
Ending balance at Dec. 31, 2023	$ (136,206)	$ 12	$ 1,350,981	$ (161)	$ (1,487,038)
Ending balance,Shares at Dec. 31, 2023		114,915,000