Condensed Consolidated Statements of Stockholders' Deficit - USD ($) $ in Thousands	Total	Common Stock [Member]	Additional Paid-In Capital [Member]	Accumulated Other Comprehensive (loss) Income [Member]	Accumulated Deficit [Member]
Beginning balance at Dec. 31, 2020	$ 50,546	$ 7	$ 1,119,632	$ 518	$ (1,069,611)
Beginning balance,Shares at Dec. 31, 2020		73,923,000
Vesting of restricted stock (in shares)		426,000
Exercise of stock options and shares issued under the employee stock purchase plan	2,849		2,849
Exercise of stock options and shares issued under the employee stock purchase plan, (shares)		365,000
Stock-based compensation expense	22,914		22,914
Issuance of common stock for asset purchase	1,355		1,355
Issuance of common stock for asset purchase (in Shares)		150,000
Issuance of common stock, net of issuance costs	9,903	$ 1	9,902
Issuance of common stock, net of issuance costs (in Shares)		638,000
Cumulative effect adjustment for adoption of new accounting guidance	(50,590)		(65,641)		15,051
Unrealized loss on investments	(240)			(240)
Foreign currency translation adjustment	94			94
Net loss	(162,808)				(162,808)
Ending balance at Sep. 30, 2021	(125,977)	$ 8	1,091,011	372	(1,217,368)
Ending balance,Shares at Sep. 30, 2021		75,502,000
Beginning balance at Jun. 30, 2021	(83,132)	$ 8	1,082,220	196	(1,165,556)
Beginning balance,Shares at Jun. 30, 2021		75,334,000
Vesting of restricted stock (in shares)		15,000
Exercise of stock options and shares issued under the employee stock purchase plan	16		16
Exercise of stock options and shares issued under the employee stock purchase plan, (shares)		3,000
Stock-based compensation expense	7,420		7,420
Issuance of common stock for asset purchase	1,355		1,355
Issuance of common stock for asset purchase (in Shares)		150,000
Unrealized loss on investments	(67)			(67)
Foreign currency translation adjustment	243			243
Net loss	(51,812)				(51,812)
Ending balance at Sep. 30, 2021	(125,977)	$ 8	1,091,011	372	(1,217,368)
Ending balance,Shares at Sep. 30, 2021		75,502,000
Beginning balance at Dec. 31, 2021	(79,673)	$ 8	1,098,776	191	(1,178,648)
Beginning balance,Shares at Dec. 31, 2021		75,746,000
Vesting of restricted stock (in shares)		844,000
Exercise of stock options and shares issued under the employee stock purchase plan	2,813		2,813
Exercise of stock options and shares issued under the employee stock purchase plan, (shares)		445,000
Stock-based compensation expense	29,226		29,226
Issuance of common stock, net of issuance costs	35,082		35,082
Issuance of common stock, net of issuance costs (in Shares)		3,992,000
Unrealized loss on investments	(329)			(329)
Foreign currency translation adjustment	(614)			(614)
Net loss	(126,785)				(126,785)
Ending balance at Sep. 30, 2022	(140,280)	$ 8	1,165,897	(752)	(1,305,433)
Ending balance,Shares at Sep. 30, 2022		81,027,000
Beginning balance at Jun. 30, 2022	(116,338)	$ 8	1,153,301	(538)	(1,269,109)
Beginning balance,Shares at Jun. 30, 2022		79,798,000
Vesting of restricted stock (in shares)		171,000
Exercise of stock options and shares issued under the employee stock purchase plan	11		11
Exercise of stock options and shares issued under the employee stock purchase plan, (shares)		7,000
Stock-based compensation expense	6,797		6,797
Issuance of common stock, net of issuance costs	5,788		5,788
Issuance of common stock, net of issuance costs (in Shares)		1,051,000
Unrealized loss on investments	(145)			(145)
Foreign currency translation adjustment	(69)			(69)
Net loss	(36,324)				(36,324)
Ending balance at Sep. 30, 2022	$ (140,280)	$ 8	$ 1,165,897	$ (752)	$ (1,305,433)
Ending balance,Shares at Sep. 30, 2022		81,027,000